Δ9-Tetrahydrocannabinol (Δ9-THC) Improves Ischemia/Reperfusion Heart Dysfunction and Might Serve as a Cardioprotective Agent in the Future Treatment

Δ9-Tetrahydrocannabinol (Δ9-THC) Improves Ischemia/Reperfusion Heart Dysfunction and Might Serve as a Cardioprotective Agent in the Future Treatment

Background: Ischemia/reperfusion (I/R) is a pivotal mechanism of organ injury during clinical stetting for example for cardiopulmonary bypasses. The generation of reactive oxygen species (ROS) during I/R induces oxidative stress that promotes endothelial dysfunction, DNA dissociation and local infla...

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Bibliographic Details
Main Authors: Marta Banaszkiewicz, Paulina Tarwacka, Anna Krzywonos-Zawadzka, Agnieszka Olejnik, Robert Laprairie, Agnieszka Noszczyk-Nowak, Grzegorz Sawicki, Iwona Bil-Lula
Format: Article
Language:English
Published: IMR Press 2022-04-01
Series:Frontiers in Bioscience-Landmark
Subjects:
ischemia-reperfusion injury
cardioprotection
9-tetrahydrocannabinol
oxidants
antioxidants
matrix metalloproteinases
contractility
inflammation
Online Access:https://www.imrpress.com/journal/FBL/27/4/10.31083/j.fbl2704114

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https://www.imrpress.com/journal/FBL/27/4/10.31083/j.fbl2704114

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