Oral Intake of Inosine 5′-Monophosphate in Mice Promotes the Absorption of Exogenous Fatty Acids and Their Conversion into Triglycerides though Enhancing the Phosphorylation of Adenosine 5′-Monophosphate-Activated Protein Kinase in the Liver, Leading to Lipohyperplasia

Oral Intake of Inosine 5′-Monophosphate in Mice Promotes the Absorption of Exogenous Fatty Acids and Their Conversion into Triglycerides though Enhancing the Phosphorylation of Adenosine 5′-Monophosphate-Activated Protein Kinase in the Liver, Leading to Lipohyperplasia

Inosine 5′-monophoaphate (IMP) is a food additive that promotes serious lipohyperplasia in the liver of C57/KsJ-<i>db</i>/<i>db</i> (<i>db</i>/<i>db</i>) mice. Thus, IMP taken orally by healthy mice might also damage their health. To date, how IMP affe...

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Bibliographic Details
Main Authors: Bin Zhang, Yang Xu, Jinyan Liu, Chongming Wu, Xiaohong Zhao, Lidong Zhou, Yong Xie
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:International Journal of Molecular Sciences
Subjects:
inosine 5′-monophosphate (IMP)
AMPK
acetyl-CoA
ACC
lipohyperplasia
Online Access:https://www.mdpi.com/1422-0067/24/19/14588

Internet

https://www.mdpi.com/1422-0067/24/19/14588

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