An individualized medication model of sodium valproate for patients with bipolar disorder based on machine learning and deep learning techniques

An individualized medication model of sodium valproate for patients with bipolar disorder based on machine learning and deep learning techniques

Valproic acid/sodium valproate (VPA) is a widely used anticonvulsant drug for maintenance treatment of bipolar disorders. In order to balance the efficacy and adverse events of VPA treatment, an individualized dose regimen is necessary. This study aimed to establish an individualized medication mode...

Full description

Bibliographic Details
Main Authors: Ping Zheng, Ze Yu, Liqian Mo, Yuqing Zhang, Chunming Lyu, Yongsheng Yu, Jinyuan Zhang, Xin Hao, Hai Wei, Fei Gao, Yilei Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Pharmacology
Subjects:
sodium valproate
individualized dose
machine learning
deep learning
CatBoost
bipolar disorder
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.890221/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.890221/full

Similar Items