Physiology of PNS axons relies on glycolytic metabolism in myelinating Schwann cells

While lactate shuttle theory states that glial cells metabolize glucose into lactate to shuttle it to neurons, how glial cells support axonal metabolism and function remains unclear. Lactate production is a common occurrence following anaerobic glycolysis in muscles. However, several other cell type...

Full description

Bibliographic Details
Main Authors: Marie Deck, Gerben Van Hameren, Graham Campbell, Nathalie Bernard-Marissal, Jérôme Devaux, Jade Berthelot, Alise Lattard, Jean-Jacques Médard, Benoît Gautier, Sophie Guelfi, Scarlette Abbou, Patrice Quintana, Juan Manuel Chao de la Barca, Pascal Reynier, Guy Lenaers, Roman Chrast, Nicolas Tricaud
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9531822/?tool=EBI