Evolutionary Insights from Association Rule Mining of Co-Occurring Mutations in Influenza Hemagglutinin and Neuraminidase

Evolutionary Insights from Association Rule Mining of Co-Occurring Mutations in Influenza Hemagglutinin and Neuraminidase

Seasonal influenza viruses continuously evolve via antigenic drift. This leads to recurring epidemics, globally significant mortality rates, and the need for annually updated vaccines. Co-occurring mutations in hemagglutinin (HA) and neuraminidase (NA) are suggested to have synergistic interactions...

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Bibliographic Details
Main Authors: Valentina Galeone, Carol Lee, Michael T. Monaghan, Denis C. Bauer, Laurence O. W. Wilson
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Viruses
Subjects:
influenza
H3N2
association rule mining
antigenic drift
co-occurring mutations
Online Access:https://www.mdpi.com/1999-4915/16/10/1515

Internet

https://www.mdpi.com/1999-4915/16/10/1515

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