Computational Insights into the Interaction between Cytoadherence Receptor gC1qR and the DBLβ12 Domain of a <i>Plasmodium falciparum</i> PfEMP1 Ligand

Computational Insights into the Interaction between Cytoadherence Receptor gC1qR and the DBLβ12 Domain of a <i>Plasmodium falciparum</i> PfEMP1 Ligand

Human receptor gC1qR is a 32 kD protein that mediates the cytoadherence of <i>Plasmodium falciparum</i>-infected erythrocytes (IEs) to human brain microvascular endothelial cells (HBMEC) and platelets. The cytoadherence of IEs to gC1qR has been associated with severe malaria symptoms. Th...

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Bibliographic Details
Main Authors: Rowaida Bakri, Mohd Rehan, Hina Shamshad, Abdul Hafiz
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Life
Subjects:
malaria
cytoadherence
gC1qR
<i>Plasmodium falciparum</i> erythrocyte membrane protein 1 (PfEMP1)
Duffy binding-like (DBL) domain
Online Access:https://www.mdpi.com/2075-1729/11/9/993

Internet

https://www.mdpi.com/2075-1729/11/9/993

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