Ipilimumab-induced colitis: experience from a tertiary referral center

Background: Ipilimumab is an anticytotoxic T-lymphocyte antigen-4 (CTLA-4) monoclonal antibody used for the treatment of malignant melanoma. It can cause immune-mediated inflammatory adverse events, including diarrhoea and even intestinal perforation or death in clinical trials but there is a dearth...

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Bibliographic Details
Main Authors: Anthony O’Connor, Maria Marples, Clive Mulatero, John Hamlin, Alexander C. Ford
Format: Article
Language:English
Published: SAGE Publishing 2016-07-01
Series:Therapeutic Advances in Gastroenterology
Online Access:https://doi.org/10.1177/1756283X16646709