Highly Pathogenic Avian Influenza H5 Hemagglutinin Fused with the A Subunit of Type IIb <i>Escherichia coli</i> Heat Labile Enterotoxin Elicited Protective Immunity and Neutralization by Intranasal Immunization in Mouse and Chicken Models

Highly pathogenic avian influenza viruses are classified by the World Organization for Animal Health (OIE) as causes of devastating avian diseases. This study aimed to develop type IIb <i>Escherichia</i> <i>coli</i> heat-labile enterotoxin (LTIIb) as novel mucosal adjuvants f...

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Bibliographic Details
Main Authors: Neos Tang, Shi-Wei Lin, Ting-Hsuan Chen, Jia-Tsrong Jan, Hung-Yi Wu, Suh-Chin Wu
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/7/4/193