In Vitro Susceptibility to Miltefosine of <i>Leishmania infantum</i> (syn. <i>L.</i> <i>chagasi</i>) Isolates from Different Geographical Areas in Brazil

In Vitro Susceptibility to Miltefosine of <i>Leishmania infantum</i> (syn. <i>L.</i> <i>chagasi</i>) Isolates from Different Geographical Areas in Brazil

Treatment of visceral leishmaniasis in Brazil still relies on meglumine antimoniate, with less than ideal efficacy and safety, making new therapeutic tools an urgent need. The oral drug miltefosine was assayed in a phase II clinical trial in Brazil with cure rates lower than previously demonstrated...

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Bibliographic Details
Main Authors: Caroline Ricce Espada, Erica V. de Castro Levatti, Mariana Côrtes Boité, Dorcas Lamounier, Jorge Alvar, Elisa Cupolillo, Carlos Henrique Nery Costa, Joelle Rode, Silvia R. B. Uliana
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Microorganisms
Subjects:
clinical strains
miltefosine
susceptibility
visceral leishmaniasis
Online Access:https://www.mdpi.com/2076-2607/9/6/1228

Internet

https://www.mdpi.com/2076-2607/9/6/1228

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