Adaptive control of the E. coli-specific growth rate in fed-batch cultivation based on oxygen uptake rate

Adaptive control of the E. coli-specific growth rate in fed-batch cultivation based on oxygen uptake rate

In this study, an automatic control system is developed for the setpoint control of the cell biomass specific growth rate (SGR) in fed-batch cultivation processes. The feedback signal in the control system is obtained from the oxygen uptake rate (OUR) measurement-based SGR estimator. The OUR online...

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Bibliographic Details
Main Authors: Renaldas Urniezius, Deividas Masaitis, Donatas Levisauskas, Arnas Survyla, Povilas Babilius, Dziuljeta Godoladze
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Fed-batch culture
Specific growth rate
Setpoint control
Adaptive control
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037023004488

Internet

http://www.sciencedirect.com/science/article/pii/S2001037023004488

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