Antibody-dependent enhancement of porcine reproductive and respiratory syndrome virus infection downregulates the levels of interferon-gamma/lambdas in porcine alveolar macrophages in vitro

Antibody-dependent enhancement of porcine reproductive and respiratory syndrome virus infection downregulates the levels of interferon-gamma/lambdas in porcine alveolar macrophages in vitro

Fc gamma receptor-mediated antibody-dependent enhancement (ADE) can promote virus invasion of target cells, sometimes exacerbating the severity of the disease. ADE may be an enormous hurdle to developing efficacious vaccines for certain human and animal viruses. ADE of porcine reproductive and respi...

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Bibliographic Details
Main Authors: Liujun Zhang, Xing Feng, Huandi Wang, Shaojun He, Hongjie Fan, Deyi Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Veterinary Science
Subjects:
PRRSV-ADE
IFN-γ
IFN-λs
TGF-β1
PAMs
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2023.1150430/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2023.1150430/full

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