Statistical evidence for the presence of trajectory in single-cell data

Abstract Background Cells progressing from an early state to a developed state give rise to lineages in cell differentiation. Knowledge of these lineages is central to developmental biology. Each biological lineage corresponds to a trajectory in a dynamical system. Emerging single-cell technologies...

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Bibliographic Details
Main Authors: Lovemore Tenha, Mingzhou Song
Format: Article
Language:English
Published: BMC 2022-08-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-022-04875-9