Use of viral motif mimicry improves the proteome-wide discovery of human linear motifs

Summary: Linear motifs have an integral role in dynamic cell functions, including cell signaling. However, due to their small size, low complexity, and frequent mutations, identifying novel functional motifs poses a challenge. Viruses rely extensively on the molecular mimicry of cellular linear moti...

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Bibliographic Details
Main Authors: Bishoy Wadie, Vitalii Kleshchevnikov, Elissavet Sandaltzopoulou, Caroline Benz, Evangelia Petsalaki
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124722005289