Searching for Frataxin Function: Exploring the Analogy with Nqo15, the Frataxin-like Protein of Respiratory Complex I from <i>Thermus thermophilus</i>

Searching for Frataxin Function: Exploring the Analogy with Nqo15, the Frataxin-like Protein of Respiratory Complex I from <i>Thermus thermophilus</i>

Nqo15 is a subunit of respiratory complex I of the bacterium <i>Thermus thermophilus</i>, with strong structural similarity to human frataxin (FXN), a protein involved in the mitochondrial disease Friedreich’s ataxia (FRDA). Recently, we showed that the expression of recombinant Nqo15 ca...

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Bibliographic Details
Main Authors: Davide Doni, Eva Cavallari, Martin Ezequiel Noguera, Hernan Gustavo Gentili, Federica Cavion, Gustavo Parisi, Maria Silvina Fornasari, Geppo Sartori, Javier Santos, Massimo Bellanda, Donatella Carbonera, Paola Costantini, Marco Bortolus
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
Friedreich’s ataxia
Frataxin
Nqo15
Online Access:https://www.mdpi.com/1422-0067/25/3/1912

Internet

https://www.mdpi.com/1422-0067/25/3/1912

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