Protective effect of antihypertensive drugs on the risk of Parkinson’s disease lacks causal evidence from mendelian randomization

Protective effect of antihypertensive drugs on the risk of Parkinson’s disease lacks causal evidence from mendelian randomization

Background: Evidence from observational studies concerning the causal role of blood pressure (BP) and antihypertensive medications (AHM) on Parkinson’s disease (PD) remains inconclusive. A two-sample Mendelian randomization (MR) study was performed to evaluate the unconfounded association of genetic...

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Bibliographic Details
Main Authors: Zheng Jiang, Xiao-Jing Gu, Wei-Ming Su, Qing-Qing Duan, Yan-Lin Ren, Ju-Rong Li, Li-Yi Chi, Yi Wang, Bei Cao, Yong-Ping Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Pharmacology
Subjects:
Parkinson’s disease
age at onset
Mendelian randomization
blood pressure
antihypertensive medications
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1107248/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1107248/full

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