Collagenase-based wound debridement agent induces extracellular matrix supporting phenotype in macrophages

Abstract Macrophages assume diverse phenotypes and functions in response to cues from the microenvironment. Earlier we reported an anti-inflammatory effect of Collagenase Santyl® Ointment (CSO) and the active constituent of CSO (CS-API) on wound macrophages in resolving wound inflammation indicating...

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Bibliographic Details
Main Authors: Pradipta Banerjee, Amitava Das, Kanhaiya Singh, Savita Khanna, Chandan K. Sen, Sashwati Roy
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-53424-2