Inhibitor discovery of full-length New Delhi metallo-β-lactamase-1 (NDM-1).

New Delhi metallo-β-lactmase-1 (NDM-1) has recently attracted extensive attention for its biological activities to catalyze the hydrolysis of almost all of β-lactam antibiotics. To study the catalytic property of NDM-1, the steady-kinetic parameters of NDM-1 toward several kinds of β-lactam antibiot...

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Bibliographic Details
Main Authors: Bingzheng Shen, Yan Yu, Hui Chen, Xin Cao, Xingzhen Lao, Yongliang Fang, Yun Shi, Jiao Chen, Heng Zheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23675445/pdf/?tool=EBI