Lycopene inhibits carrageenan-induced thrombi by regulating AKT/FoxO3a and TLR4/NF-κB pathways

Lycopene inhibits carrageenan-induced thrombi by regulating AKT/FoxO3a and TLR4/NF-κB pathways

Lycopene (LYC) is a natural phytonutrient with various bioactivities, such as anti-oxidative stress and anti-inflammation. In this study, human endothelial cells (HUVECs), macrophages and human platelets, and carrageenan-induced thrombosis mouse model were used to evaluate the antithrombosis effects...

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Bibliographic Details
Main Authors: Rong Huang, Yingquan Liang, Jiukang Feng, Zhouling Xie, Qingshan Li, Yuanli Chen, Yajun Duan, Hui Liu, Buchun Zhang, Chenzhong Liao, Xiaoxiao Yang
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Journal of Functional Foods
Subjects:
Inflammation
Lycopene
Platelet
ROS
Thrombus
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464624000239

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http://www.sciencedirect.com/science/article/pii/S1756464624000239

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