Near-perfect control of the regioselective glucosylation enabled by rational design of glycosyltransferases

Regioselective syntheses of glycosides using modern chemical methods suffer from the need to invoke multiple steps of protection and deprotection, and even then product mixtures may occur. Discovering and tuning by mutagenesis glycosyltransferases (GTs) with considerable substrate promiscuity is an...

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Bibliographic Details
Main Authors: Jiao Li, Ge Qu, Na Shang, Peng Chen, Yan Men, Weidong Liu, Zelong Mei, Yuanxia Sun, Zhoutong Sun
Format: Article
Language:English
Published: KeAi Communications Co. Ltd. 2021-02-01
Series:Green Synthesis and Catalysis
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666554921000053