Cooperative kinetics of ligand binding to linear polymers

Cooperative kinetics of ligand binding to linear polymers

Ligands change the chemical and mechanical properties of polymers. In particular, single strand binding protein (SSB) non-specifically bounds to single-stranded DNA (ssDNA), modifying the ssDNA stiffness and the DNA replication rate, as recently measured with single-molecule techniques. SSB is a lar...

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Bibliographic Details
Main Authors: Juan P.G. Villaluenga, Francisco Javier Cao-García
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Cooperativity
Ligand binding
SSB
DNA
RNA
Polymer
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022000083

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http://www.sciencedirect.com/science/article/pii/S2001037022000083

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