Drug Responses in Plexiform Neurofibroma Type I (PNF1) Cell Lines Using High-Throughput Data and Combined Effectiveness and Potency

Drug Responses in Plexiform Neurofibroma Type I (PNF1) Cell Lines Using High-Throughput Data and Combined Effectiveness and Potency

<i>Background</i>: Neurofibromatosis type 1 (NF1) is a genetic disorder characterized by heterozygous germline <i>NF1</i> gene mutations that predispose patients to developing plexiform neurofibromas, which are benign but often disfiguring tumors of the peripheral nerve sheat...

Full description

Bibliographic Details
Main Authors: Paul O. Zamora, Gabriel Altay, Ulisses Santamaria, Nathan Dwarshuis, Hari Donthi, Chang In Moon, Dana Bakalar, Matthew Zamora
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Cancers
Subjects:
neurofibromatosis
NF1
high-throughput
plexiform
drug evaluation
in vitro
Online Access:https://www.mdpi.com/2072-6694/15/24/5811

Internet

https://www.mdpi.com/2072-6694/15/24/5811

Similar Items