Necrotic neurons enhance microglial neurotoxicity through induction of glutaminase by a MyD88-dependent pathway
<p>Abstract</p> <p>Background</p> <p>Microglia are macrophage-like cells that constantly sense the microenvironment within the central nervous system (CNS). In the event of neuronal stress or injury, microglial cells rapidly react and change their phenotype. This respon...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2008-10-01
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| Series: | Journal of Neuroinflammation |
| Online Access: | http://www.jneuroinflammation.com/content/5/1/43 |