Crystal structures reveal the multi-ligand binding mechanism of Staphylococcus aureus ClfB.

Staphylococcus aureus (S. aureus) pathogenesis is a complex process involving a diverse array of extracellular and cell wall components. ClfB, an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules) family surface protein, described as a fibrinogen-binding clumping factor, is...

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Bibliographic Details
Main Authors: Hua Xiang, Yue Feng, Jiawei Wang, Bao Liu, Yeguang Chen, Lei Liu, Xuming Deng, Maojun Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3375286?pdf=render