Improved determination of plasmid copy number using quantitative real-time PCR for monitoring fermentation processes
<p>Abstract</p> <p>Background</p> <p>Recombinant protein production in <it>Escherichia coli </it>cells is a complex process, where among other parameters, plasmid copy number, structural and segregational stability of plasmid have an important impact on the...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-03-01
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Series: | Microbial Cell Factories |
Online Access: | http://www.microbialcellfactories.com/content/7/1/6 |