Nrf2 plays a critical role in the metabolic response during and after spaceflight

Nrf2 plays a critical role in the metabolic response during and after spaceflight

Akira Uruno et al. report the volume of epidydimal white adipose tissue and plasma glycerophospholipid and sphingolipid levels in mice increase during spaceflight. These metabolic and physiological changes were largely driven by Nrf2 (NF-E2-related factor-2), ultimately providing a mechanistic targe...

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Bibliographic Details
Main Authors: Akira Uruno, Daisuke Saigusa, Takafumi Suzuki, Akane Yumoto, Tomohiro Nakamura, Naomi Matsukawa, Takahiro Yamazaki, Ristumi Saito, Keiko Taguchi, Mikiko Suzuki, Norio Suzuki, Akihito Otsuki, Fumiki Katsuoka, Eiji Hishinuma, Risa Okada, Seizo Koshiba, Yoshihisa Tomioka, Ritsuko Shimizu, Masaki Shirakawa, Thomas W. Kensler, Dai Shiba, Masayuki Yamamoto
Format: Article
Language:English
Published: Nature Portfolio 2021-12-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02904-6

Internet

https://doi.org/10.1038/s42003-021-02904-6

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