Curdlan (<i>Alcaligenes faecalis</i>) (1→3)-β-<span style="font-variant: small-caps">d</span>-Glucan Oligosaccharides Drive M1 Phenotype Polarization in Murine Bone Marrow-Derived Macrophages via Activation of MAPKs and NF-κB Pathways

Curdlan (<i>Alcaligenes faecalis</i>) (1→3)-β-<span style="font-variant: small-caps">d</span>-Glucan Oligosaccharides Drive M1 Phenotype Polarization in Murine Bone Marrow-Derived Macrophages via Activation of MAPKs and NF-κB Pathways

Functional oligosaccharides, particularly curdlan (1&#8594;3)-&#946;-<span style="font-variant: small-caps;">d</span>-glucan oligosaccharides (GOS), play important roles in modulating host immune responses. However, the molecular mechanisms underlying the immunostimulat...

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Bibliographic Details
Main Authors: Jun Liu, Jiqing Tang, Xiuting Li, Qiaojuan Yan, Junwen Ma, Zhengqiang Jiang
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Molecules
Subjects:
curdlan (1→3)-β-<span style="font-variant: small-caps">d</span>-glucan oligosaccharides
macrophage polarization
mitogen-activated protein kinases
nuclear factor-kappa b
receptor blocking
Online Access:https://www.mdpi.com/1420-3049/24/23/4251

Internet

https://www.mdpi.com/1420-3049/24/23/4251

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