Inhibitory effect of truncated isoforms on GPCR dimerization predicted by combinatorial computational strategy
G protein-coupled receptors (GPCRs) play a pivotal role in fundamental biological processes and disease development. GPCR isoforms, derived from alternative splicing, can exhibit distinct signaling patterns. Some highly-truncated isoforms can impact functional performance of full-length receptors, s...
| Main Authors: | , , , , |
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| 格式: | 文件 |
| 语言: | English |
| 出版: |
Elsevier
2024-12-01
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| 丛编: | Computational and Structural Biotechnology Journal |
| 主题: | |
| 在线阅读: | http://www.sciencedirect.com/science/article/pii/S2001037023004828 |