Rubrofusarin Attenuates Chronic Restraint Stress-Induced Depressive Symptoms

Rubrofusarin Attenuates Chronic Restraint Stress-Induced Depressive Symptoms

The aim of this study was to examine whether rubrofusarin, an active ingredient of the Cassia species, has an antidepressive effect in chronic restraint stress (CRS) mouse model. Although acute treatment using rubrofusarin failed, chronic treatment using rubrofusarin ameliorated CRS-induced depressi...

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Bibliographic Details
Main Authors: Jee Hyun Yi, Jieun Jeon, Huiyoung Kwon, Eunbi Cho, Jeanho Yun, Young Choon Lee, Jong Hoon Ryu, Se Jin Park, Jong Hyun Cho, Dong Hyun Kim
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
rubrofusarin
depressive disorder
chronic restraint stress
neuroinflammation
Akt
synaptic plasticity
Online Access:https://www.mdpi.com/1422-0067/21/10/3454

Internet

https://www.mdpi.com/1422-0067/21/10/3454

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