HiCAT: a tool for automatic annotation of centromere structure

Abstract Significant improvements in long-read sequencing technologies have unlocked complex genomic areas, such as centromeres, in the genome and introduced the centromere annotation problem. Currently, centromeres are annotated in a semi-manual way. Here, we propose HiCAT, a generalizable automati...

Full description

Bibliographic Details
Main Authors: Shenghan Gao, Xiaofei Yang, Hongtao Guo, Xixi Zhao, Bo Wang, Kai Ye
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-023-02900-5