Model-Guided Metabolic Rewiring for Gamma-Aminobutyric Acid and Butyrolactam Biosynthesis in <i>Corynebacterium</i> <i>glutamicum</i> ATCC13032

Gamma-aminobutyric acid (GABA) can be used as a bioactive component in the pharmaceutical industry and a precursor for the synthesis of butyrolactam, which functions as a monomer for the synthesis of polyamide 4 (nylon 4) with improved thermal stability and high biodegradability. The bio-based ferme...

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Bibliographic Details
Main Authors: Yun Zhang, Jing Zhao, Xueliang Wang, Yuan Tang, Shuwen Liu, Tingyi Wen
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/11/6/846