Tropomyosin receptor kinase B (TrkB) signalling: targeted therapy in neurogenic tumours
Abstract Tropomyosin receptor kinase B (TrkB), a transmembrane receptor protein, has been found to play a pivotal role in neural development. This protein is encoded by the neurotrophic receptor tyrosine kinase 2 (NTRK2) gene, and its abnormal activation caused by NTRK2 overexpression or fusion can...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2023-03-01
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Series: | The Journal of Pathology: Clinical Research |
Subjects: | |
Online Access: | https://doi.org/10.1002/cjp2.307 |