Tropomyosin receptor kinase B (TrkB) signalling: targeted therapy in neurogenic tumours

Abstract Tropomyosin receptor kinase B (TrkB), a transmembrane receptor protein, has been found to play a pivotal role in neural development. This protein is encoded by the neurotrophic receptor tyrosine kinase 2 (NTRK2) gene, and its abnormal activation caused by NTRK2 overexpression or fusion can...

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Bibliographic Details
Main Authors: Yuehua Li, Chengjiang Wei, Wei Wang, Qingfeng Li, Zhi‐Chao Wang
Format: Article
Language:English
Published: Wiley 2023-03-01
Series:The Journal of Pathology: Clinical Research
Subjects:
Online Access:https://doi.org/10.1002/cjp2.307