Unraveling the role of VLDL in the relationship between type 2 diabetes and coronary atherosclerosis: a Mendelian randomization analysis

Unraveling the role of VLDL in the relationship between type 2 diabetes and coronary atherosclerosis: a Mendelian randomization analysis

BackgroundThe causal link between Type 2 diabetes (T2D) and coronary atherosclerosis has been established through wet lab experiments; however, its analysis with Genome-wide association studies (GWAS) data remains unexplored. This study aims to validate this relationship using Mendelian randomizatio...

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Bibliographic Details
Main Authors: Wenshuai Feng, Liuli Guo, Yiman Liu, Ming Ren
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
type 2 diabetes
very low-density lipoprotein
coronary atherosclerosis
Mendelian randomization
mediation pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1234271/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2023.1234271/full

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