Vitamin D Receptor Protects against Radiation-Induced Intestinal Injury in Mice via Inhibition of Intestinal Crypt Stem/Progenitor Cell Apoptosis

Vitamin D Receptor Protects against Radiation-Induced Intestinal Injury in Mice via Inhibition of Intestinal Crypt Stem/Progenitor Cell Apoptosis

It is urgent to seek new potential targets for the prevention or relief of gastrointestinal syndrome in clinical radiation therapy for cancers. Vitamin D, mediated through the vitamin D receptor (VDR), has been identified as a protective nutrient against ionizing radiation (IR)-induced damage. This...

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Bibliographic Details
Main Authors: Wusun Li, Yingying Lin, Yujia Luo, Yuqi Wang, Yao Lu, Yixuan Li, Huiyuan Guo
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Nutrients
Subjects:
apoptosis
crypt stem/progenitor cell
ionizing radiation
Pmaip1
vitamin D/vitamin D receptor
Online Access:https://www.mdpi.com/2072-6643/13/9/2910

Internet

https://www.mdpi.com/2072-6643/13/9/2910

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