Altered methylation of imprinted genes in neuroblastoma: implications for prognostic refinement

Altered methylation of imprinted genes in neuroblastoma: implications for prognostic refinement

Abstract Background Neuroblastoma (NB) is a complex disease, and the current understanding of NB biology is limited. Deregulation in genomic imprinting is a common event in malignancy. Since imprinted genes play crucial roles in early fetal growth and development, their role in NB pathogenesis could...

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Bibliographic Details
Main Authors: Medha Suman, Maja Löfgren, Susanne Fransson, Jewahri Idris Yousuf, Johanna Svensson, Anna Djos, Tommy Martinsson, Per Kogner, Teresia Kling, Helena Carén
Format: Article
Language:English
Published: BMC 2024-08-01
Series:Journal of Translational Medicine
Subjects:
Neuroblastoma
Genomic imprinting
DNA methylation
Copy number alterations
Online Access:https://doi.org/10.1186/s12967-024-05634-5

Internet

https://doi.org/10.1186/s12967-024-05634-5

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