Chikungunya virus exploits miR-146a to regulate NF-κB pathway in human synovial fibroblasts.

OBJECTIVES: Chikungunya virus causes chronic infection with manifestations of joint pain. Human synovial fibroblasts get infected with CHIKV and could lead to pro-inflammatory responses. MicroRNAs have potentials to regulate the gene expression of various anti-viral and pro-inflammatory genes. The s...

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Bibliographic Details
Main Authors: Sakthi Priya Selvamani, Ritu Mishra, Sunit K Singh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4118904?pdf=render