mitoSomatic: a tool for accurate identification of mitochondrial DNA somatic mutations without paired controls

mitoSomatic: a tool for accurate identification of mitochondrial DNA somatic mutations without paired controls

Mitochondrial DNA (mtDNA) somatic mutations play important roles in the initiation and progression of cancer. Although next‐generation sequencing (NGS) of paired tumor and control samples has become a common practice to identify tumor‐specific mtDNA mutations, the unique nature of mtDNA and NGS‐asso...

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Bibliographic Details
Main Authors: Wenjie Guo, Yang Liu, Liping Su, Shanshan Guo, Fanfan Xie, Xiaoying Ji, Kaixiang Zhou, Xu Guo, Xiwen Gu, Jinliang Xing
Format: Article
Language:English
Published: Wiley 2023-05-01
Series:Molecular Oncology
Subjects:
machine learning
mitochondrial DNA
next‐generation sequencing
somatic mutations
Online Access:https://doi.org/10.1002/1878-0261.13335

Internet

https://doi.org/10.1002/1878-0261.13335

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