Linking LOXL2 to Cardiac Interstitial Fibrosis

Linking LOXL2 to Cardiac Interstitial Fibrosis

Cardiovascular diseases (CVDs) are the leading causes of death worldwide. CVD pathophysiology is often characterized by increased stiffening of the heart muscle due to fibrosis, thus resulting in diminished cardiac function. Fibrosis can be caused by increased oxidative stress and inflammation, whic...

Full description

Bibliographic Details
Main Authors: Melisse Erasmus, Ebrahim Samodien, Sandrine Lecour, Martin Cour, Oscar Lorenzo, Phiwayinkosi Dludla, Carmen Pheiffer, Rabia Johnson
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
Lysyl Oxidase-Like 2 (LOXL2)
epigenetics
DNA methylation
fibrosis
cardiovascular disease (CVD)
Online Access:https://www.mdpi.com/1422-0067/21/16/5913

Internet

https://www.mdpi.com/1422-0067/21/16/5913

Similar Items