Genetic confounds of transgenerational epigenetic inheritance in mice

Transgenerational epigenetic inheritance in mammals remains a controversial phenomenon. A recent study by Takahashi et al. provides evidence for this mode of inheritance in mice by using a CRISPR/Cas9-based epigenetic editing technique to modify DNA methylation levels at specific promoters and then...

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Bibliographic Details
Main Authors: Daniel M. Sapozhnikov, Moshe Szyf
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Epigenetics
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/15592294.2024.2318519