The Active Constituent From Gynostemma Pentaphyllum Prevents Liver Fibrosis Through Regulation of the TGF-β1/NDRG2/MAPK Axis

The Active Constituent From Gynostemma Pentaphyllum Prevents Liver Fibrosis Through Regulation of the TGF-β1/NDRG2/MAPK Axis

Liver fibrosis resulting from chronic liver damage constitutes a major health care burden worldwide; however, no antifibrogenic agents are currently available. Our previous study reported that the small molecule NPLC0393 extracted from the herb Gynostemma pentaphyllum exerts efficient antifibrotic e...

Full description

Bibliographic Details
Main Authors: Hui Huang, Kuifeng Wang, Qian Liu, Feihong Ji, Hu Zhou, Shanhua Fang, Jiansheng Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Genetics
Subjects:
HSC
TGF-β1
liver fibrosis
quantitative proteomics
NDRG2
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.594824/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2020.594824/full

Similar Items