The Active Constituent From Gynostemma Pentaphyllum Prevents Liver Fibrosis Through Regulation of the TGF-β1/NDRG2/MAPK Axis

Liver fibrosis resulting from chronic liver damage constitutes a major health care burden worldwide; however, no antifibrogenic agents are currently available. Our previous study reported that the small molecule NPLC0393 extracted from the herb Gynostemma pentaphyllum exerts efficient antifibrotic e...

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Hlavní autoři: Hui Huang, Kuifeng Wang, Qian Liu, Feihong Ji, Hu Zhou, Shanhua Fang, Jiansheng Zhu
Médium: Článek
Jazyk:English
Vydáno: Frontiers Media S.A. 2020-11-01
Edice:Frontiers in Genetics
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fgene.2020.594824/full