Genome Mining, Heterologous Expression, Antibacterial and Antioxidant Activities of Lipoamides and Amicoumacins from Compost-Associated <i>Bacillus subtilis</i> fmb60

Genome Mining, Heterologous Expression, Antibacterial and Antioxidant Activities of Lipoamides and Amicoumacins from Compost-Associated <i>Bacillus subtilis</i> fmb60

<i>Bacillus subtilis</i> fmb60, which has broad-spectrum antimicrobial activities, was isolated from plant straw compost. A hybrid NRPS/PKS cluster was screened from the genome. Sixteen secondary metabolites produced by the gene cluster were isolated and identified using LC-HRMS and NMR....

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Bibliographic Details
Main Authors: Jie Yang, Qingzheng Zhu, Feng Xu, Ming Yang, Hechao Du, Xiaoying Bian, Zhaoxin Lu, Yingjian Lu, Fengxia Lu
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Molecules
Subjects:
<i>Bacillus subtilis</i>
NRPS<b>/</b>PKS
amicoumacins
heterologous expression
bioactivities
Online Access:https://www.mdpi.com/1420-3049/26/7/1892

Internet

https://www.mdpi.com/1420-3049/26/7/1892

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