YTHDF2-mediated circYAP1 drives immune escape and cancer progression through activating YAP1/TCF4-PD-L1 axis

YTHDF2-mediated circYAP1 drives immune escape and cancer progression through activating YAP1/TCF4-PD-L1 axis

Summary: Immune escape is identified as one of the reasons for the poor prognosis of colorectal cancer (CRC) patients. Circular RNAs are considered to promote tumor progression by mediating tumor immune escape. We discovered that higher expression of circYAP1 was associated with a worse prognosis of...

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Bibliographic Details
Main Authors: Zhuang Chen, Wenkang Wang, Shengyun Hu, Haifeng Sun, Chen Chen, Zhiyong Zhang, Xinzhi Sun, Bin Jia, Junhong Hu, Chengzeng Wang, Yang Liu, Zhenqiang Sun
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:iScience
Subjects:
Molecular biology
Immunology
Cell biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223028560

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http://www.sciencedirect.com/science/article/pii/S2589004223028560

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