Interferon-Gamma Modulation of the Local T Cell Response to Alphavirus Encephalomyelitis

Interferon-Gamma Modulation of the Local T Cell Response to Alphavirus Encephalomyelitis

Infection of mice with Sindbis virus (SINV) provides a model for examining the role of the immune response to alphavirus infection of the central nervous system (CNS). Interferon-gamma (IFN-γ) is an important component of this response, and we show that SINV-infected differentiated neurons...

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Bibliographic Details
Main Authors: Victoria K. Baxter, Diane E. Griffin
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Viruses
Subjects:
sindbis virus
viral encephalomyelitis
viral rna clearance
interferon-gamma
t cells
nk cells
granzyme b
Online Access:https://www.mdpi.com/1999-4915/12/1/113

Internet

https://www.mdpi.com/1999-4915/12/1/113

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