Organismal and Cellular Stress Responses upon Disruption of Mitochondrial Lonp1 Protease

Organismal and Cellular Stress Responses upon Disruption of Mitochondrial Lonp1 Protease

Cells engage complex surveillance mechanisms to maintain mitochondrial function and protein homeostasis. LonP1 protease is a key component of mitochondrial quality control and has been implicated in human malignancies and other pathological disorders. Here, we employed two experimental systems, the...

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Bibliographic Details
Main Authors: Eirini Taouktsi, Eleni Kyriakou, Stefanos Smyrniotis, Fivos Borbolis, Labrina Bondi, Socratis Avgeris, Efstathios Trigazis, Stamatis Rigas, Gerassimos E. Voutsinas, Popi Syntichaki
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cells
Subjects:
mitochondria
LonP1
aging
cancer
CDDO-Me
<i>C. elegans</i>
Online Access:https://www.mdpi.com/2073-4409/11/8/1363

Internet

https://www.mdpi.com/2073-4409/11/8/1363

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