Identification and characterization of methylation-mediated transcriptional dysregulation dictate methylation roles in preeclampsia

Identification and characterization of methylation-mediated transcriptional dysregulation dictate methylation roles in preeclampsia

Abstract Background Preeclampsia (PE) is a heterogeneous, hypertensive disorder of pregnancy, with no robust biomarkers or effective treatments. PE increases the risk of poor outcomes for both the mother and the baby. Methylation-mediated transcriptional dysregulation motifs (methTDMs) could contrib...

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Bibliographic Details
Main Authors: Shuyu Zhao, Nan Lv, Yan Li, Tianyi Liu, Yuhong Sun, Xiaodan Chu
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Human Genomics
Subjects:
Preeclampsia
Methylation
Transcriptional dysregulation
Drug repurposing
Biomarker
Online Access:https://doi.org/10.1186/s40246-020-0256-9

Internet

https://doi.org/10.1186/s40246-020-0256-9

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