Production of zosteric acid and other sulfated phenolic biochemicals in microbial cell factories

Toxicity and limited solubility inhibits the biological production of many organic compounds. Here the authors metabolically engineer sulfate uptake and activation in order to produce sulfate esters of phenolic compounds, such as zosteric acid, thereby addressing these issues.

Bibliographic Details
Main Authors: Christian Bille Jendresen, Alex Toftgaard Nielsen
Format: Article
Language:English
Published: Nature Portfolio 2019-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-12022-x