Nanoparticle-Mediated Angiotensin-(1-9) Drug Delivery for the Treatment of Cardiac Hypertrophy

Nanoparticle-Mediated Angiotensin-(1-9) Drug Delivery for the Treatment of Cardiac Hypertrophy

Ang-(1-9) peptide is a bioactive vasodilator peptide that prevents cardiomyocyte hypertrophy in vitro and in vivo as well as lowers blood pressure and pathological cardiovascular remodeling; however, it has a reduced half-life in circulation, requiring a suitable carrier for its delivery. In this wo...

Full description

Bibliographic Details
Main Authors: Sabrina Sepúlveda-Rivas, Matías S. Leal, Zully Pedrozo, Marcelo J. Kogan, María Paz Ocaranza, Javier O. Morales
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Pharmaceutics
Subjects:
polymeric nanoparticles
gold nanoparticles
angiotensin-(1-9)
peptide delivery
cardiac hypertrophy
Online Access:https://www.mdpi.com/1999-4923/13/6/822

Internet

https://www.mdpi.com/1999-4923/13/6/822

Similar Items