PD-1 regulates neural damage in oligodendroglia-induced inflammation.

PD-1 regulates neural damage in oligodendroglia-induced inflammation.

We investigated the impact of immune regulatory mechanisms involved in the modulation of the recently presented, CD8+ lymphocyte mediated immune response in a mouse model of oligodendropathy-induced inflammation (PLPtg-mutants). The focus was on the role of the co-inhibitory molecule PD-1, a CD28-re...

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Bibliographic Details
Main Authors: Antje Kroner, Nicholas Schwab, Chi Wang Ip, Christoph Leder, Klaus-Armin Nave, Mathias Mäurer, Heinz Wiendl, Rudolf Martini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19197390/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19197390/?tool=EBI

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