TLR3 activation by Clonorchis sinensis infection alleviates the fluke-induced liver fibrosis.

Clonorchis sinensis is a zoonotic parasite associated with liver fibrosis and cholangiocarcinoma development. The role of toll-like receptors (TLRs) in C. sinensis infection has not yet been fully elucidated. Here, the TLR3 signaling pathway, cytokine expression and liver fibrosis were examined in C...

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Bibliographic Details
Main Authors: Yuru Wang, Pengtao Gong, Xuancheng Zhang, Xiaocen Wang, Xu Zhang, Nan Zhang, Yanhui Yu, Yeting Ma, Haoyang Zhang, Xichen Zhang, Xin Li, Jianhua Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-05-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0011325