Pre-clinical Studies Identifying Molecular Pathways of Neuroinflammation in Parkinson's Disease: A Systematic Review

Pre-clinical Studies Identifying Molecular Pathways of Neuroinflammation in Parkinson's Disease: A Systematic Review

Parkinson's disease (PD), the second most common neurodegenerative disorder, is characterized by neuroinflammation, formation of Lewy bodies, and progressive loss of dopaminergic neurons in the substantia nigra of the brain. In this review, we summarize evidence obtained by animal studies demon...

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Bibliographic Details
Main Authors: Mobina Fathi, Kimia Vakili, Shirin Yaghoobpoor, Mohammad Sadegh Qadirifard, Mohammadreza Kosari, Navid Naghsh, Afsaneh Asgari taei, Andis Klegeris, Mina Dehghani, Ashkan Bahrami, Hamed Taheri, Ashraf Mohamadkhani, Ramtin Hajibeygi, Mostafa Rezaei Tavirani, Fatemeh Sayehmiri
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
Parkinson's disease
nuclear factor kappa B (NF-κB)
NLRP3 inflammasome
microglia
mast cells
neuroinflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.855776/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2022.855776/full

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